Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus.

Devika RanadeRoopali PradhanMuhunden JayakrishnanSushmitha HegdeKundan Sengupta

Published in: BMC molecular and cell biology (2019)

Taken together, these studies underscore a remarkable interplay between Lamin A/C and Emerin in modulating cytoskeletal organization of actin and NM1 that impinges on chromatin dynamics and function in the interphase nucleus.

Keyphrases

dna damage
gene expression
transcription factor
genome wide
signaling pathway
cell migration