Dupilumab-induced hypereosinophilia: review of the literature and algorithm proposal for clinical management.

Marco CaminatiBianca OlivieriAnnarita DamaClaudio MichelettoPierluigi PaggiaroPatrick PinterGianenrico SennaMichele Schiappoli

Published in: Expert review of respiratory medicine (2022)

Dealing with dupilumab-induced hypereosinophilia represents a clinical challenge for clinicians managing patients on dupilumab therapy. An algorithm for the practical management of dupilumab-induced hypereosinophilia has been proposed, in order to properly investigate potential eosinophil-related morbidity and avoid unnecessary drug discontinuation.

Keyphrases

atopic dermatitis
high glucose
diabetic rats
drug induced
machine learning
emergency department
newly diagnosed
palliative care
prognostic factors
stem cells
risk assessment
bone marrow
mesenchymal stem cells
climate change
patient reported outcomes
cell therapy
patient reported