Using osmotic stress to stabilize mannitol production in Synechocystis sp. PCC6803.
Wenyang WuWei DuRuth Perez GallegoKlaas J HellingwerfAniek D van der WoudeFilipe Branco Dos SantosPublished in: Biotechnology for biofuels (2020)
Mannitol production in freshwater Synechocsytis sp. PCC6803 confers it with increased salt tolerance. Under this strategy, genetically instability which was the major challenge for mannitol production in cyanobacteria is tackled. This paper marks the first report of utilization of the response to salt stress as a factor that can increase the stability of mannitol production in a cyanobacterial cell factory.
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