Activation of aryl hydrocarbon receptor signaling by a novel agonist ameliorates autoimmune encephalomyelitis.
Alzahrani AbdullahMohammed MagedIbrahim Hairul-Islam MAlwassil Osama IHabash MahaAlfuwaires ManalHanieh HamzaPublished in: PloS one (2019)
Our findings identify GA as a novel Ahr ligand and provide molecular mechanisms elucidating the ameliorative effects of GA on EAE, suggesting that GA is a potential therapeutic agent to control inflammation in autoimmune diseases such as MS.