Pityriasis rubra pilaris-like graft-vs-host disease following allogeneic stem cell transplant in two patients.
Jennifer Y WangMika M TabataSilvina PuglieseDarci PhillipsJinah KimWen-Kai WengBernice Y KwongPublished in: Clinical case reports (2019)
Chronic cutaneous graft-vs-host disease (GVHD) has several atypical variants. We describe two cases of GVHD with clinical and histopathologic features of pityriasis rubra pilaris (PRP), which responded to additional immunosuppression. Recognition of this newly described PRP-like clinical presentation of GVHD may prompt early consideration of additional steroid-sparing therapies.
Keyphrases
- stem cells
- allogeneic hematopoietic stem cell transplantation
- end stage renal disease
- ejection fraction
- stem cell transplantation
- chronic kidney disease
- bone marrow
- platelet rich plasma
- prognostic factors
- acute lymphoblastic leukemia
- copy number
- gene expression
- dna methylation
- genome wide
- high dose
- cell therapy
- hematopoietic stem cell
- drug induced