Drug-drug interaction between dexamethasone and direct-acting oral anticoagulants: a nested case-control study in the National COVID Cohort Collaborative (N3C).

Olga V KravchenkoRichard D BoyceAinhoa Gomez-LumbrerasPaul T KocisLorenzo Villa ZapataMalinda TanCharles E LeonardKathleen M AndersenHemalkumar B MehtaG Caleb AlexanderDaniel C Malonenull null

Published in: BMJ open (2022)

This nested case-control study did not find evidence of an association between concomitant exposure to dexamethasone and a DOAC with an increase in risk of TEE. Due to small sample size, an association cannot be completely ruled out.

Keyphrases

oral anticoagulants
quality improvement
atrial fibrillation
coronavirus disease
high dose
low dose
sars cov
case control
adverse drug
direct oral anticoagulants
drug induced
venous thromboembolism
electronic health record