Next-generation sequencing in pediatric-onset epilepsies: Analysis with target panels and personalized therapeutic approach.
Barbara CastellottiFrancesca RagonaElena FreriGiuliana MessinaStefania MagriRoberto PrevitaliRoberta SolazziSilvana FranceschettiFranco TaroniCanafoglia LauraCinzia GelleraTiziana GranataDiFrancesco Jacopo CosimoPublished in: Epilepsia open (2024)
The analysis of patients with pediatric-onset epilepsy using advanced technologies for the screening of all the implicated genes allows the identification of the cause of diseases in an ever-increasing number of cases. Understanding the pathogenic mechanisms could, in some cases, guide the selection and optimization of appropriate treatment approaches for patients.