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Next-generation sequencing in pediatric-onset epilepsies: Analysis with target panels and personalized therapeutic approach.

Barbara CastellottiFrancesca RagonaElena FreriGiuliana MessinaStefania MagriRoberto PrevitaliRoberta SolazziSilvana FranceschettiFranco TaroniCanafoglia LauraCinzia GelleraTiziana GranataDiFrancesco Jacopo Cosimo
Published in: Epilepsia open (2024)
The analysis of patients with pediatric-onset epilepsy using advanced technologies for the screening of all the implicated genes allows the identification of the cause of diseases in an ever-increasing number of cases. Understanding the pathogenic mechanisms could, in some cases, guide the selection and optimization of appropriate treatment approaches for patients.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • prognostic factors
  • peritoneal dialysis
  • genome wide
  • gene expression
  • transcription factor
  • patient reported
  • childhood cancer