Downregulation of ATP6V1A Involved in Alzheimer's Disease via Synaptic Vesicle Cycle, Phagosome, and Oxidative Phosphorylation.

Zhike ZhouJun BaiShanshan ZhongRongwei ZhangKexin KangXiaoqian ZhangYing XuChuansheng Zhao Mei Zhao

Published in: Oxidative medicine and cellular longevity (2021)

Our findings highlighted the pleiotropic roles of low ATP6V1A in AD pathogenesis, possibly mediated by synaptic vesicle cycle, phagosome, and oxidative phosphorylation.

Keyphrases

protein kinase
prefrontal cortex
cell proliferation
signaling pathway
cognitive decline