Orally administered gold nanoparticles protect against colitis by attenuating Toll-like receptor 4- and reactive oxygen/nitrogen species-mediated inflammatory responses but could induce gut dysbiosis in mice.
Suqin ZhuXiumei JiangMary D BoudreauGuangxin FengYu MiaoShiyuan DongHaohao WuMingyong ZengJun-Jie YinPublished in: Journal of nanobiotechnology (2018)
AuNPs have promising potential as anti-inflammatory agents; however, their therapeutic applications via the oral route may have a negative impact on the gut microbiota.