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Aptamer-Based Cancer Cell Analysis and Treatment.

Limei WuYutong ZhangZhimin WangYue ZhangJianmei ZouLiping Qiu
Published in: ChemistryOpen (2022)
Aptamers are a class of single-stranded DNA or RNA oligonucleotides that can exclusively bind to various targets with high affinity and selectivity. Regarded as "chemical antibodies", aptamers possess several intrinsic advantages, including easy synthesis, convenient modification, high programmability, and good biocompatibility. In recent decades, many studies have demonstrated the superiority of aptamers as molecular tools for various biological applications, particularly in the area of cancer theranostics. In this review, we focus on recent progress in developing aptamer-based strategies for the precise analysis and treatment of cancer cells.
Keyphrases
  • nucleic acid
  • gold nanoparticles
  • squamous cell carcinoma
  • single molecule
  • cell free
  • young adults
  • binding protein
  • replacement therapy
  • squamous cell
  • smoking cessation
  • data analysis