Assessment of Telomere Length and Mitochondrial DNA Copy Number in Granulosa Cells as Predictors of Aneuploidy Rate in Young Patients.
Tzu-Ning YuEn-Hui ChengHan-Ni TsaiPin-Yao LinChien-Hong ChenChun-Chia HuangTsung-Hsien LeeMaw-Sheng LeePublished in: Journal of clinical medicine (2022)
TL in the granulosa cells was negatively correlated with the aneuploidy rate in the young-age group, supporting the application of PGT-A in younger women.
Keyphrases
- mitochondrial dna
- copy number
- induced apoptosis
- polycystic ovary syndrome
- cell cycle arrest
- end stage renal disease
- genome wide
- chronic kidney disease
- dna methylation
- newly diagnosed
- ejection fraction
- endoplasmic reticulum stress
- middle aged
- signaling pathway
- prognostic factors
- cell death
- oxidative stress
- skeletal muscle