Towards quantitative perfusion MRI of the lung in COPD: The problem of short-term repeatability.
Alvard Ter-KarapetyanSimon M F TriphanBertram J JobstAngela F AnjorinJulia Ley-ZaporozhanSebastian LeyOliver SedlaczekJürgen BiedererHans-Ulrich KauczorPeter M JakobMark O WielpützPublished in: PloS one (2018)
The second injection (RA) yielded higher PBF and PBV, which apparently contradicts the established hypothesis that hyperoxia increases lung perfusion. Quantification of 4D perfusion MRI by current software approaches may thus be limited by residual circulating contrast agent in the short-term and even the next day.