Diabetic ketoacidosis in patients with type 2 diabetes treated with sodium glucose co-transporter 2 inhibitors versus other antihyperglycemic agents: An observational study of four US administrative claims databases.
Lu WangErica A VossJames WeaverLaura HesterZhong YuanFrank DeFalcoMartijn J SchuemiePatrick B RyanDon SunAmy FreedmanMaria AlbaJoan LindGary MeiningerJesse A BerlinNorman RosenthalPublished in: Pharmacoepidemiology and drug safety (2019)
Increased risk of DKA was observed for new users of SGLT2i versus several non-SGLT2i AHAs when T2DM was defined broadly. When T2DM was defined narrowly to exclude possible misclassified patients, an increased risk of DKA with SGLT2i was observed compared with sulfonylureas.