When Should Lymphadenectomy Be Performed in Non-Metastatic Pancreatic Neuroendocrine Tumors? A Population-Based Analysis of the German Clinical Cancer Registry Group.
Thaer S A AbdallaLouisa BolmMonika Klinkhammer-SchalkeSylke Ruth ZeissigKees Kleihues van TolPeter BronsertStanislav LitkevychKim C HonselmannRüdiger BraunJudith GebauerRichard HummelTobias KeckUlrich Friedrich WellnerSteffen DeichmannPublished in: Cancers (2024)
LNM is an independent negative prognostic factor for DFS in pNETs. Due to the low incidence of LNM in T1 tumors (5%), parenchyma-sparing surgery seems oncologically adequate in small G1 pNETs, while regional lymphadenectomy should be recommended in T2 or G2/G3 pNETs.
Keyphrases
- prognostic factors
- neuroendocrine tumors
- robot assisted
- lymph node metastasis
- papillary thyroid
- minimally invasive
- lymph node
- early stage
- squamous cell carcinoma
- sentinel lymph node
- small cell lung cancer
- coronary artery bypass
- risk factors
- squamous cell
- neoadjuvant chemotherapy
- coronary artery disease
- young adults