Association of Ovar-DRB1 alleles with innate immune responses in sheep.

Atefeh EsmailnejadVahid GanjianiElhamsadat Hosseini-NasabSaeed Nazifi

Published in: Veterinary medicine and science (2021)

These results provide additional support for the association between Ovar-DRB1 alleles and regulation of immune responses in sheep population. Description of MHC polymorphism and its role in the controlling of immune responses will increase our understanding of host-pathogen interactions, and ultimately facilitate the selection of disease-resistant flocks in genetic breeding programs.

Keyphrases

immune response
dendritic cells
toll like receptor
genome wide
gene expression
copy number
inflammatory response