Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies.
Calvin R JustusEdward J SanderlinLixue DongTianai SunJen-Tsan ChiKvin LertpiriyapongLi V YangPublished in: Journal of translational medicine (2017)
This study provides data to support the concept that TDAG8 functions as a contextual tumor suppressor down-regulated in hematological malignancies and potentiation of the TDAG8 receptor pathway may be explored as a potential anti-tumorigenic approach in blood cancers.