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Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies.

Calvin R JustusEdward J SanderlinLixue DongTianai SunJen-Tsan ChiKvin LertpiriyapongLi V Yang
Published in: Journal of translational medicine (2017)
This study provides data to support the concept that TDAG8 functions as a contextual tumor suppressor down-regulated in hematological malignancies and potentiation of the TDAG8 receptor pathway may be explored as a potential anti-tumorigenic approach in blood cancers.
Keyphrases
  • cell death
  • electronic health record
  • copy number
  • machine learning
  • cell cycle arrest
  • dna methylation
  • human health
  • signaling pathway
  • deep learning
  • artificial intelligence