Survival outcomes in elderly Taiwanese women according to breast cancer subtype and lymph node status: A single-center retrospective study.
Kung-Hung LinHuan-Ming HsuKuo-Feng HsuChi-Hong ChuZhi-Jie HongChun-Yu FuYu-Ching ChouGolshan MehraMing-Shen DaiJyh-Cherng YuGuo-Shiou LiaoPublished in: PloS one (2021)
This study aimed to determine the rates of overall survival and recurrence-free survival among elderly Taiwanese women (>65 years old) according to breast cancer subtype and lymph node status. We identified 554 eligible patients who were >65 years old and had been treated based on international recommendations at our center between June 2005 and June 2015. Patients with the luminal A subtype had the highest rates of overall survival (90.6%) and recurrence-free survival (97.0%), while the lowest overall survival rate was observed in those with the triple-negative subtype (81.3%) and the lowest recurrence-free survival rate was observed in those with the luminal B subtype (84.0%). Multivariate Cox proportional hazard analysis, using the luminal A subtype as the reference, revealed significant differences in recurrence-free survival among luminal B patients according to lymph node status. Among elderly Taiwanese women with breast cancer, the breast cancer subtype might help predict survival outcomes. The luminal B subtype was associated with poor recurrence-free survival, and lymph node status was useful for predicting recurrence-free survival in this subset of patients.
Keyphrases
- free survival
- lymph node
- end stage renal disease
- newly diagnosed
- neoadjuvant chemotherapy
- ejection fraction
- chronic kidney disease
- sentinel lymph node
- prognostic factors
- middle aged
- polycystic ovary syndrome
- peritoneal dialysis
- adipose tissue
- community dwelling
- skeletal muscle
- metabolic syndrome
- young adults
- single cell
- childhood cancer