Clinical and EEG factors associated with antiseizure medication resistance in idiopathic generalized epilepsy.
Brad K KamitakiMubeen JanmohamedPadmaja KandulaChristopher ElderRam ManiStephen WongPiero PeruccaTerence J O'BrienHaiqun LinGary A HeimanHyunmi ChoiPublished in: Epilepsia (2021)
Multiple clinical and EEG characteristics independently predict ASM resistance in IGE. To improve understanding of a patient's prognosis, clinicians could consider asking about specific seizure-type combinations and track whether they experience catamenial epilepsy. Obtaining prolonged EEG studies to record the burden of GSWs in sleep and assessing for the presence of GPTs may provide additional predictive value.