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The radiosensitizing effect of β-Thujaplicin, a tropolone derivative inducing S-phase cell cycle arrest, in head and neck squamous cell carcinoma-derived cell lines.

Markus HaasTeresa LenzLorenz Kadletz-WankeGregor HeiduschkaBernhard J Jank
Published in: Investigational new drugs (2022)
ß-Thujaplicin acts as a radiosensitizer in HNSCC cell lines. Further evaluation of its use in HNSCC therapy is warranted.
Keyphrases
  • cell cycle arrest
  • cell death
  • pi k akt
  • signaling pathway
  • stem cells