Importance of the second SARS-CoV-2 vaccination dose for achieving serological response in patients with rheumatoid arthritis and seronegative spondyloarthritis.
Elisabeth SimaderSelma TobudicPeter MandlHelmuth HaslacherThomas PerkmannThomas NothnaglJudith SautnerHelga RadnerFlorian WinklerHeinz BurgmannDaniel MrakDaniel AletahaStefan WinklerStephan BlümlPublished in: Annals of the rheumatic diseases (2021)
Patients with inflammatory joint diseases under DMARD therapy show impaired humoral responses to the first vaccine dose but excellent final responses to vaccination with mRNA vaccines. Therefore, the full course of two immunisations is necessary for efficient vaccination responses in patients with inflammatory arthritis under DMARD therapy.