Small peptide CSF fingerprint of amyotrophic lateral sclerosis.

Rea LumiSusanne PetriJustyna Siwy Latosinska AgnieszkaJulia RaadPetra ZürbigThomas SkripuletzHarald MischakJoachim Beige

Published in: PloS one (2024)

Most striking deregulations in CSF from ALS patients were found in VGF, Osteopontin, SOD-1 and EFEMP1 peptides. No associations of disease severity, duration and region of onset with sequenced peptides were found.

Keyphrases

amyotrophic lateral sclerosis
end stage renal disease
ejection fraction
chronic kidney disease
peritoneal dialysis
amino acid
patient reported outcomes