Adiponectin levels in the serum and cerebrospinal fluid of amyotrophic lateral sclerosis patients: possible influence on neuroinflammation?
Patrizia BossolascoRaffaella CancelloAlberto DorettiClaudia MorelliVincenzo SilaniLidia CovaPublished in: Journal of neuroinflammation (2017)
Opposite serum APN levels are gender-related in ALS and altered in several neurological disorders, with the highest values in FTD, which shares with ALS several overlapping and neuropathological features. Further investigations are needed to clarify the possible involvement of APN in neuroinflammation and neurodegeneration. Possible involvement of APN in neuroinflammatory neurodegenerative diseases.
Keyphrases
- amyotrophic lateral sclerosis
- cerebrospinal fluid
- end stage renal disease
- ejection fraction
- traumatic brain injury
- lipopolysaccharide induced
- chronic kidney disease
- newly diagnosed
- metabolic syndrome
- cognitive impairment
- peritoneal dialysis
- prognostic factors
- mental health
- type diabetes
- insulin resistance
- skeletal muscle
- brain injury
- patient reported outcomes