Metabolomics-based multidimensional network biomarkers for diabetic retinopathy identification in patients with type 2 diabetes mellitus.

Jing-Jing ZuoYuan LanHonglin HuXiangqing HouJushuang LiTao WangHang ZhangNana ZhangChengnan GuoFang PengShuzhen ZhaoYaping WeiChaonan JiaChao ZhengGuangyun Mao

Published in: BMJ open diabetes research & care (2021)

This study demonstrates that metabolomics-based MDNBs are associated with the presence of DR and capable of distinguishing DR from T2DM efficiently. Our data also provide new insights into the mechanisms of DR and the potential value for new treatment targets development. Additional studies are needed to confirm our findings.

Keyphrases

diabetic retinopathy
editorial comment
mass spectrometry
electronic health record
big data
metabolic syndrome
case control
psychometric properties
weight loss