Nephrin as a biomarker of sickle cell glomerulopathy in Malawi.
Jonathan Brett HeimlichGodwin ChipokaLaila ElsherifEmeraghi DavidGraham EllisPortia KamthunziRobert KrysiakPilirani MafungaQingning ZhouJianwen CaiSatish GopalNigel S KeyKenneth I AtagaPublished in: Pediatric blood & cancer (2018)
These data suggest that a substantial number of children with SCD in Malawi have renal disease and could be at risk for worsening nephropathy and ESRD as they age. Our data suggest that urinary nephrin could be utilized as an early marker of glomerular disease in SCD.