Natural history of prostate cancer on active surveillance: stratification by MRI using the PRECISE recommendations in a UK cohort.

Francesco GigantiArmando StabileVasilis StavrinidesElizabeth OsinibiAdam RetterClément OrczykValeria PanebiancoBruce J TrockAlex FreemanAiman HaiderShonit PunwaniClare AllenAlex KirkhamMark EmbertonCaroline M Moore

Published in: European radiology (2020)

• Patients without radiological progression on MRI (PRECISE 1-3) during AS had a very low likelihood of clinical progression and many could avoid routine re-biopsy. • Clinical progression was almost always detectable in patients with radiological progression on MRI (PRECISE 4-5) during AS. • Patients with radiological progression on MRI (PRECISE 4-5) during AS showed a trend to an increase in PSA density.

Keyphrases

prostate cancer
contrast enhanced
magnetic resonance imaging
diffusion weighted imaging
newly diagnosed
computed tomography
clinical practice
magnetic resonance
chronic kidney disease
patient reported