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An unusual case of seizures in a 5-year-old Syrian female with abdominal tuberculosis: an isoniazid therapeutic dose side effect.

Lava MohammadLeen Jamel DoyaRazan OmranAlexander Ali IbrahimZuheir AlshehabiAli Ibrahim
Published in: Oxford medical case reports (2021)
Isoniazid (INH) is highly bactericidal against replicating tubercule bacilli and is involved in all antituberculous chemotherapeutic regimens. Several neurological adverse effects, following both therapeutic and overdose use of INH, have been reported in adults in the literature. Here, we present a case of a 5-year-old girl with intestinal Tuberculosis, who developed hemiclonic seizure as a side effect of INH therapeutic dose after 2 weeks of tuberculosis therapy.
Keyphrases
  • mycobacterium tuberculosis
  • pulmonary tuberculosis
  • hiv aids
  • systematic review
  • stem cells
  • gram negative
  • blood brain barrier
  • brain injury
  • cerebral ischemia
  • subarachnoid hemorrhage
  • replacement therapy