Visfatin Induces Inflammation and Insulin Resistance via the NF-κB and STAT3 Signaling Pathways in Hepatocytes.
Yu Jung HeoSung-E ChoiJa Young JeonSeung Jin HanDae Jung KimYup KangKwan-Woo LeeHae Jin KimPublished in: Journal of diabetes research (2019)
Visfatin induced proinflammatory cytokine production and inhibited insulin signaling via the STAT3 and NF-κB pathways in HepG2 cells.
Keyphrases
- signaling pathway
- pi k akt
- oxidative stress
- insulin resistance
- type diabetes
- cell proliferation
- lps induced
- diabetic rats
- epithelial mesenchymal transition
- induced apoptosis
- nuclear factor
- high glucose
- adipose tissue
- drug induced
- liver injury
- glycemic control
- metabolic syndrome
- high fat diet
- inflammatory response
- toll like receptor
- weight loss