Timing and rate of spheno-occipital synchondrosis closure and its relationship to puberty.
Anwar S AlhazmiEduardo VargasJ Martin PalomoMark HansBruce LatimerScott SimpsonPublished in: PloS one (2017)
There is a significant relationship between puberty onset and SOS closure, suggesting its closure is at least partially affected by systemic, hormonal changes in the growing adolescent. Also, SOS closure occurs at a faster rate and at an earlier age in females compared to males.