Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network.
Olivia WagemannYan LiJason HassenstabAndrew J AschenbrennerNicole S McKayBrian A GordonTammie L S BenzingerChengjie XiongCarlos CruchagaAlan E RentonRichard J PerrinSarah B BermanJasmeer P ChhatwalMartin R FarlowGregory S DayTakeshi IkeuchiMathias JuckerFrancisco LoperaHiroshi MoriJames M NobleRaquel Sánchez-VallePeter R SchofieldJohn C MorrisAlisha DanielsJohannes LevinRandall J BatemanEric McDadeJorge J Llibre-Guerranull nullPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)
Our findings suggest an initial cognitive reserve in female carriers followed by a pronounced increase in neurodegeneration coupled with worse performance on delayed recall at later stages of DIAD.
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