Association of interleukin-17A rs2275913 polymorphism with rheumatoid arthritis susceptibility in Sudanese population.

Rgda Mohamed OsmanMounkaila NomaAbdallah Elssir AhmedHanadi AbdelbagiRihab Ali OmerMusab M AliAyman Ali Mohammed AlameenAli Mahmoud EdrisMohamed S MuneerOmayma SiddigRowa HassanEiman Siddig AhmedLamis Ahmed HassanOsama El Hadi BakheetAyman AhmedNouh Saad MohamedEmmanuel Edwar Siddig

Published in: SAGE open medicine (2021)

This study is the first study in Sudan established the association between interleukin-17A-197G/A (rs2275913) polymorphisms and susceptibly to rheumatoid arthritis. These findings appeal for further research in Sudan to investigate the exact role of IL-17A in immunopathology and disease severity among Sudanese rheumatoid arthritis.

Keyphrases

rheumatoid arthritis
disease activity
interstitial lung disease
ankylosing spondylitis
systemic lupus erythematosus
systemic sclerosis
molecular dynamics
idiopathic pulmonary fibrosis