Dual inhibition of BTLA and PD-1 can enhance therapeutic efficacy of paclitaxel on intraperitoneally disseminated tumors.

Wei-Zen SunHan-Wei LinWan-Yu ChenChung-Liang ChienYen-Ling LaiJung ChenYu Li ChenWen-Fang Cheng

Published in: Journal for immunotherapy of cancer (2023)

Dual blockade of BTLA on B cells and PD-1 on cytotoxic T cells may have clinical potential for enhancing the efficacy of PTX in the treatment of tumors with intraperitoneal spread, including epithelial ovarian carcinomas.

Keyphrases

high grade
combination therapy
human health
climate change
anti inflammatory