Effects of artemether on pancreatic islet morphology, islet cell turnover and α-cell transdifferentiation in insulin-deficient GluCreERT2;ROSA26-eYFP diabetic mice.

Dipak SarnobatRyan A LaffertyR Charlotte MoffettAndrei I TarasovPeter R FlattNigel Irwin

Published in: The Journal of pharmacy and pharmacology (2022)

Our observations confirm that artemisinin derivatives do not impart meaningful benefits on islet cell lineage transition events or pancreatic islet morphology.

Keyphrases

single cell
cell therapy
type diabetes
adipose tissue
skeletal muscle
mesenchymal stem cells
structure activity relationship