First-trimester maternal serum biomarkers and the risk of cerebral palsy.
Monique PerisSusan M ReidStephen DobieLeo BonacquistoDaisy A ShepherdDavid J AmorPublished in: Developmental medicine and child neurology (2020)
Low first-trimester levels of biomarkers in maternal serum are associated with later cerebral palsy (CP). Early pregnancy factors have potential importance in causal pathways to CP. Causal pathways involving preterm birth, term neonatal encephalopathy, and genetic syndromes may be implicated.