Fomepizole dosing during continuous renal replacement therapy - an observational study.

Yvonne Elisabeth LaoTrond VartdalSten FroeyshovBrian LatimerChristiane KvaernerMarija MataricPeter HolmSiri ForeidDag JacobsenKenneth McMartinKnut Erik Hovda

Published in: Clinical toxicology (Philadelphia, Pa.) (2021)

Fomepizole was eliminated during CCRT. The new dosing recommendations for fomepizole and CRRT appeared safe, by maintaining the plasma concentration above the minimum value of 10 µmol/L. Based on these data, the fomepizole maintenance dose during CRRT could be reduced to half as compared to intermittent hemodialysis.

Keyphrases

acute kidney injury
chronic kidney disease
peritoneal dialysis
end stage renal disease
big data
data analysis