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Pharmacokinetic profile and physiological effects of oral and compounded intravenous gabapentin in goats.

Renata S CostaChristine M WinslowCharles A VeltriMaria LozoyaJeffrey W Norris
Published in: Veterinary anaesthesia and analgesia (2024)
Gabapentin is well-absorbed following oral administration to goats but yielded significantly lower serum concentrations than the IV route. The longer half-life of gabapentin following oral than after IV administration may result from prolonged absorption throughout the caprine gastrointestinal tract. IV gabapentin may cause slight ataxia in some goats.
Keyphrases
  • neuropathic pain
  • spinal cord
  • spinal cord injury
  • low dose