Acute pancreatitis induced by methimazole treatment in a 51-year-old korean man: a case report.
Jung Hwa JungJong Ryeal HahmJaehoon JungSoo Kyoung KimSungsu KimKyong Young KimBo Ra KimHong Jun KimYi Yeong JeongSun Joo KimPublished in: Journal of Korean medical science (2014)
Methimazole (MMI)-induced acute pancreatitis is very rare but severe adverse reaction. A 51-yr-old male developed a high fever, chills, and abdominal pain, two weeks after commencement on MMI for the treatment of Graves' disease. There was no evidence of agranulocytosis, and fever subsided soon after stopping MMI treatment. However, 5 hr after taking an additional dose of MMI, abdominal pain and fever developed again. His symptoms, biochemical, and imaging studies were compatible with acute pancreatitis. After withdrawal of MMI, he showed clinical improvement. This is the first case of MMI-induced acute pancreatitis in Korea. Clinicians should be aware of the rare but possible MMI-induced pancreatitis in patients complaining of fever and abdominal pain.
Keyphrases
- abdominal pain
- high glucose
- diabetic rats
- end stage renal disease
- emergency department
- palliative care
- chronic kidney disease
- high resolution
- ejection fraction
- newly diagnosed
- oxidative stress
- physical activity
- prognostic factors
- endothelial cells
- early onset
- replacement therapy
- sleep quality
- gestational age
- stress induced
- patient reported
- adverse drug