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Causal links between sedentary behavior, physical activity, and psychiatric disorders: a Mendelian randomization study.

Hongjun BaLili ZhangHuimin PengXiufang HeYao Wang
Published in: Annals of general psychiatry (2024)
The study provides compelling evidence of a link between depression, bipolar disorder, and excessive TV watching. Furthermore, it suggests that higher accelerometer-assessed fraction accelerations of >ā€‰425 milligravities can serve as a genetic protective factor against depression. To mitigate the risk of developing depression, it is advisable to reduce sedentary activities, particularly television watching, and prioritize engaging in vigorous physical exercise.
Keyphrases
  • physical activity
  • bipolar disorder
  • depressive symptoms
  • sleep quality
  • body mass index
  • gene expression
  • weight gain
  • copy number