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Lewis Acid-Facilitated Radiofluorination of MN3PU: A LRRK2 Radiotracer.

Noeen MalikShreya BendreRalf SchirrmacherPaul Schaffer
Published in: Molecules (Basel, Switzerland) (2020)
RCYs of [18F]FMN3PU (7) improved from ~5% using conventional nucleophilic radiofluorination, up to 41 ± 1% using Lewis-acid supported SNAr.
Keyphrases
  • pet imaging
  • room temperature
  • computed tomography
  • metal organic framework
  • ionic liquid