18 F-labeled 1,2,3-triazole-linked Glu-urea-Lys-based PSMA ligands have good pharmacokinetic properties for positron emission tomography imaging of prostate cancer.

Byoung Se LeeSo Young ChuWoon Jung JungHyeon Jin JeongKyongkyu LeeMin Hwan KimMi Hyun KimDae Yoon ChiHeesu AhnYong Jin LeeKyo Chul LeeSang Moo Lim

Published in: The Prostate (2020)

[18 F]6c showed significant tumor uptake, a high tumor-to-nontumor ratio, and good radiation dosimetry results, suggesting further development as a potential diagnostic PET agent for prostate cancer.

Keyphrases

positron emission tomography
prostate cancer
pet imaging
pet ct
computed tomography
radical prostatectomy
high resolution
mass spectrometry
fluorescence imaging
human health
risk assessment