Assessing the need for systematic biopsies in addition to targeted biopsies according to the characteristics of the index lesion at mpMRI. Results from a large, multi-institutional database.
Francesco BarlettaElio MazzoneArmando StabileSimone ScuderiGiorgio BrembillaMario de AngelisGiuseppe Ottone CirulliVito CucchiaraGiorgio GandagliaR Jeffrey KarnesMorgan RoupretFrancesco De CobelliFrancesco MontorsiAlberto BrigantiPublished in: World journal of urology (2022)
Increasing IL volume in PI-RADS 3 and 4 lesions is associated with reduction in SBx csPCa added value. For diagnostic purposes, SBx could be omitted in men with IL larger than 1.2 ml and 0.6 ml for PI-RADS 3 and 4, respectively. Conversely, for PI-RADS 5, SBx csPCa added value was minimal regardless of IL volume.