Presenting Features in 269 Patients With Clinically Nonfunctioning Pituitary Adenomas Enrolled in a Prospective Study.
Pamela U FredaJeffrey N BruceAlexander G KhandjiZhezhen JinRichard A HickmanEmily FreyCarlos Reyes-VidalMarc OttenSharon L WardlawKalmon D PostPublished in: Journal of the Endocrine Society (2020)
Patients with CNFPAs commonly present incidentally and with previously unrecognized hypopituitarism and symptoms that could have prompted earlier diagnosis. Our data support screening all large micro and macro-CNFPAs for hypopituitarism. Most patients with CNFPAs still have mass effect signs at presentation, suggesting the need for more awareness of pituitary disease. Our ongoing, prospective observation of this cohort will assess outcomes of these CNFPA groups.