GATA4-Twist1 Signalling in Disturbed Flow-Induced Atherosclerosis.

Marwa MahmoudCeline SouilholJovana Serbanovic-CanicPaul Evans

Published in: Cardiovascular drugs and therapy (2020)

We revealed that GATA4-Twist1-Snail signalling triggers EC dysfunction and atherosclerosis; this work could lead to the development of novel anti-atherosclerosis therapeutics.

Keyphrases

epithelial mesenchymal transition
cardiovascular disease
transcription factor
oxidative stress
small molecule
high glucose
diabetic rats
endothelial cells