Predicting CAR-T cell Immunotherapy Success through ImmunoPET.
Alessia VolpeVeronica L NagleJason S LewisVladimir PonomarevPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Chimeric antigen receptor (CAR)-T cell therapy has generated unprecedented advances in the treatment of hematologic cancers, but readily translatable imaging approaches to visualize the in vivo dynamics of CAR-T cells are lacking. Noninvasive PET imaging is the ideal tool to monitor CAR-T cells.See related article by Simonetta et al., p. 1058.