HER2 Overexpression as a Poor Prognostic Determinant in Resected Biliary Tract Cancer.

Caterina VivaldiLorenzo FornaroClara UgoliniCristina NiccoliGianna MusettiniIrene PecoraAndrea Cacciato InsillaFrancesca SalaniGiulia PasquiniSilvia CataneseMonica LencioniGianluca MasiDaniela CampaniGabriella FontantiniAlfredo FalconeEnrico Vasile

Published in: The oncologist (2020)

HER2 overexpression may play an independent role in promoting an aggressive behavior in resectable biliary tract cancer. This evidence could be helpful in improving prognostic stratification after resection and, primarily, should endorse the rationale to investigate HER2 as a therapeutic target in biliary tract cancer.

Keyphrases

papillary thyroid
squamous cell
cell proliferation
transcription factor
clinical trial
squamous cell carcinoma
lymph node metastasis
childhood cancer
radiation therapy
young adults
prognostic factors