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Evaluation of confounding in epidemiologic studies assessing alcohol consumption on the risk of ischemic heart disease.

Joshua D WallachStylianos SerghiouLingzhi ChuAlexander C EgilmanVasilis VasiliouJoseph S RossJohn P A Ioannidis
Published in: BMC medical research methodology (2020)
There is large variation in the confounders considered across observational studies evaluating the impact of alcohol on ischemic heart disease risk and almost all studies spuriously ignore or eventually dismiss confounding in their conclusions. Given that study results and interpretations may be affected by the mix of potential confounders included within multivariate models, efforts are necessary to standardize approaches for selecting and accounting for confounders in observational studies.
Keyphrases
  • alcohol consumption
  • case control
  • quality improvement