Topical fluoride-antibacterial agent combined therapy versus topical fluoride monotherapy in preventing dental caries: a systematic review and meta-analysis.
Arpit GuptaS Shardanull NishantN ShafiqA KumarA GoyalPublished in: European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry (2020)
The pooled analysis indicates towards an added benefit of topical fluoride-antibacterial agent combined therapy over topical fluoride monotherapy in preventing dental caries incidence among children. However, the results may be interpreted with caution since the evidence generated is of low certainty and is driven by two studies on Xylitol, thus it demands further good quality trials.