A Multifunctional Nano-Delivery System Against Rheumatoid Arthritis by Combined Phototherapy, Hypoxia-Activated Chemotherapy, and RNA Interference.

Xiangyu LiShixin ZhangMiaomiao ZhangGe LiBo YangXinyue LuLesheng TengYouxin LiFengying Sun

Published in: International journal of nanomedicine (2022)

Overall, these FA-functionalized, pH-responsive PFHNs/TM represent a promising platform for the co-delivery of chemical drugs and nucleic acids for the treatment of RA cooperating with NIR-induced phototherapy.

Keyphrases

rheumatoid arthritis
disease activity
high glucose
drug delivery
endothelial cells
ankylosing spondylitis
diabetic rats
drug induced
high throughput
quantum dots
locally advanced
radiation therapy
high resolution
single cell
metal organic framework
systemic sclerosis