Boosting the Brain Delivery of Atazanavir through Nanostructured Lipid Carrier-Based Approach for Mitigating NeuroAIDS.

Saif Ahmad KhanSaleha RehmanBushra NabiAshif IqubalNida NehalUsama Ahmed Fahmy Sabna Kotta Sanjula Baboota Shadab Md Javed Ali

Published in: Pharmaceutics (2020)

Thus, NLC could be a promising avenue for encapsulating hydrophobic drugs and delivering it to their target site. The results suggested that increase in bioavailability and brain-targeted delivery by NLC, in all plausibility, help in improving the therapeutic prospects of atazanavir.

Keyphrases

resting state
white matter
hiv infected patients
functional connectivity
cerebral ischemia
ionic liquid
brain injury