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One-Step Electrochemical Growth of 2D/3D Zn(II)-MOF Hybrid Nanocomposites on an Electrode and Utilization of a PtNPs@2D MOF Nanocatalyst for Electrochemical Immunoassay.

Daili TangXiaolan YangBirui WangYanbin DingSiyu XuJunjie LiuYang PengXinglong YuZhaohong SuXiaoli Qin
Published in: ACS applied materials & interfaces (2021)
To date, two-dimensional (2D) and three-dimensional (3D) metal organic frameworks (MOFs) have been promising materials for applications in electrocatalysis, separation, and sensing. However, the exploration of a simple method for simultaneous fabrication of 2D/3D MOFs on a surface remains challenging. Herein, a one-step and in situ electrosynthesis strategy for fabrication of 2D Hemin-bridged MOF sheets (Hemin-MOFs) or 2D/3D Zn(II)-MOF hybrid nanocomposites on an electrode is reported. It exhibits varied morphologies at different electrodeposition times and attains a 2D/3D complex morphology by adding 1,3,5-benzenetricarboxylic acid (H3BTC) as an organic ligand. The morphology and size of 2D Hemin-MOFs are important factors that influence their performance. Since Pt nanoparticles (PtNPs) are grown on 2D Hemin-MOF sheets, this composite can serve as the peroxidase mimics and PtNPs can act as an anchor to capture the antibody. Therefore, this hybrid nanosheet-modified electrode is used as an electrochemical sensing platform for ultrasensitive pig immunoglobulin G (IgG) and the surface-protective antigen (Spa) protein of Erysipelothrix rhusiopathiae immunodetection. Moreover, this work provides a new avenue for the electrochemical synthesis of 2D/3D MOF hybrid nanocomposites with a high surface area and biomimetic catalysts.
Keyphrases
  • metal organic framework
  • gold nanoparticles
  • label free
  • carbon nanotubes
  • molecularly imprinted
  • reduced graphene oxide
  • ionic liquid
  • tissue engineering
  • binding protein
  • small molecule
  • protein protein