Mutational landscape differences between young-onset and older-onset breast cancer patients.
Nicole E MealeyDylan E O'SullivanJoy PaderYibing RuanEdwin WangMay Lynn QuanDarren R BrennerPublished in: BMC cancer (2020)
The results of this exploratory study provide some evidence that the mutational landscape and mutational signatures among young-onset breast cancer are different from those of older-onset patients. The characterization of young-onset tumours could provide clues to their etiology which may inform future prevention. Further studies are required to confirm our findings.