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Mutational landscape differences between young-onset and older-onset breast cancer patients.

Nicole E MealeyDylan E O'SullivanJoy PaderYibing RuanEdwin WangMay Lynn QuanDarren R Brenner
Published in: BMC cancer (2020)
The results of this exploratory study provide some evidence that the mutational landscape and mutational signatures among young-onset breast cancer are different from those of older-onset patients. The characterization of young-onset tumours could provide clues to their etiology which may inform future prevention. Further studies are required to confirm our findings.
Keyphrases
  • middle aged
  • end stage renal disease
  • physical activity
  • chronic kidney disease
  • newly diagnosed
  • peritoneal dialysis
  • prognostic factors
  • gene expression
  • community dwelling
  • current status